Publications

Please find below a list of current publications relating to the Head & Neck 5000 study.  Further publications are in progress; please revisit the website for updates.

 

 

2019

 

Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP. et al. Shared heritability and functional enrichment across six solid cancersNat Commun. 2019 Jan 25;10(1):431.

 

Lang S, Schimansky S, Beynon R, Penfold C, Davies A, Waylen A, Thomas S, Pring M, Pawlita M, Waterboer T, Ness AR. Dietary behaviors and survival in people with head and neck cancer: Results from Head and Neck 5000. Head Neck. 2019 Jan 30. doi:10.1002/hed.25660. [Epub ahead of print]

 

 

2018

 

Ambatipudi S, Langdon R, Richmond RC, Suderman M, Koestler DC, Kelsey KT, Kazmi N, Penfold C, Ho KM, McArdle W, Ring SM, Pring M, Waterboer T, Pawlita M, Gaunt TR, Davey Smith G, Thomas S, Ness AR, Relton CL. DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival. Oral Oncol 2018; 85: 87-94.

 

Beynon RA, Lang S, Schimansky S, Penfold CM, Waylen A, Thomas SJ, Pawlita M, Waterboer T T, Martin RM, May M, Ness AR. Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: Results from Head and Neck 5000, a prospective observational cohort of people with head and neck cancer. Int J Cancer 2018; 143: 1114-1127.

 

Dudding T, Johansson M, Thomas SJ, Brennan P, Martin RM, Timpson NJ. Assessing the causal association between

25-hydroxyvitamin D and the risk of oral and oropharyngeal cancer using Mendelian randomization Int J Cancer 2018; 143: 1029-1036. 

 

Jansen F, Verdonck-de Leeuw IM, Cuijpers P, Leemans CR, Waterboer T, Pawlita M, Penfold C, Thomas SJ, Waylen A, Ness AR. Depressive symptoms in relation to overall survival in people with head and neck cancer: a longitudinal cohort study. Psychooncology 2018; 27: 2245-2256. 

 

Kachuri L. Saarele O. Bojesen S. et al Mendelian Randomization and mediation analysis of leukocyte telomere length

and risk of lung and head and neck cancers  Int J Epidemiol 2018 [Epub ahead of print]

 

Penfold CM, Thomas SJ, Waylen A, Ness AR. Change in alcohol and tobacco consumption after a diagnosis of head and neck cancer: Findings from Head and Neck 5000. Head Neck 2018; 40: 1389-1399.

 

Schimansky S, Lang S, Beynon R, Penfold C, Davies A, Waylen A, Thomas S, Pring M, Pawlita M, Waterboer T, Ness A. 

Association between comorbidity and survival in head and neck cancer: Results from Head and Neck 5000

Head Neck. 2018; doi: 10.1002/hed.25543. [Epub ahead of print]

 

Thomas SJ, Penfold CM, Waylen A, Ness AR. The changing aetiology of head and neck squamous cell cancer: a tale of three cancers? Clin Otolaryngol 2018; 10.1111/coa.13144

 

 

2016

 

Lesseur C, Diergaarde B, Olshan AF, Wunsch-Filho V, Ness AR, Liu G, Lacko M, Eluf-Nato J, Franceschi S, Lagiou P, Macfarlane GJ, Richiardi L, Boccia S, Polesei J, Kjaerheim K, Zaridze D, Johansson M, Weissler MC, Tajara EH, Nunes FD, de carvalho MB, Thomas S, Hung RJ, Peters WH, Herrero R, Cadoni G, Bueno-de-Mesquita HB, Steffen A, Agudo A, Shangina O, Xiao X, Gaborieau V, Chabrier A, Anantharaman D, Boffetta P, Amos CI, McKay JD, Brennan P.  Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.

Nature Genetics 2016: 48: 1544-1550

 

 

2015

 

Ness AR, Waylen A, Jeffreys M, Penfold C, Pring M, Leary S, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W
Worthington H, Nutting C, Fisher SO, Rogers SN, Thomas SJ; Head & Neck Study Team. Recruitment response rates and characteristics of 5511 enrolled in a perspective clinical cohort study head & neck 5000. Clinical Otolaryngology 2015; 41: 804-809.

 

 

2014

 

Ness AR, Waylen A, Hurley K, Jeffreys M, Penfold C, Pring M, Leary S, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W, Worthington H, Nutting C, Fisher S, Rogers SN, Thomas SJ, Head & Neck 5000 Study Team.   Establishing a large prospective clinical cohort in people with head and neck cancer as a biomedical resource : head and neck 5000. BMC Cancer 2014; 14: 973

 

 

2012

 

Hughes C, Homer J, Bradley P, Nutting C, Ness A, Persson M, Jefferys M,Waylen, A, Leary S, Thomas S. An evaluation of current services available for people diagnosed with Head and Neck Cancer in the UK (2009-2010). Clin Oncol 2012; 24: e187-92.