Please find below a list of current publications relating to the Head & Neck 5000 study.  Further publications are in progress; please revisit the website for updates.



Jansen F, Verdonck-de Leeuw IM, Cuijpers P, Leemans CR, Waterboer T, Pawlita M, Penfold C, Thomas SJ, Waylen A, Ness AR. Depressive symptoms in relation to overall survival in people with head and neck cancer: a longitudinal cohort study. Psycho-oncology. 2018 Jun 21. doi: 10.1002/pon.4816. [Epub ahead of print]


Kachuri L. Saarele O. Bojesen S. et al Mendelian Randomization and mediation analysis of leukocyte telomere length

and risk of lung and head and neck cancers  International Journal of Epidemiology 2018 July 28. PMID: 30059977

DOI: 10.1093/ije/dyy140. [Epub ahead of print]


Thomas SJ, Penfold CM, Waylen A, Ness AR. The changing aetiology of head and neck squamous cell cancer: a tale of three cancers? Clin Otolaryngol. 2018 May 16. doi: 10.1111/coa.13144. [Epub ahead of print]


Dudding T, Johansson M, Thomas SJ, Brennan P, Martin RM, Timpson NJ. Assessing the causal association between

25-hydroxyvitamin D and the risk of oral and oropharyngeal cancer using Mendelian randomization Int J Cancer. 2018 Mar 14. doi: 10.1002/ijc.31377. [Epub ahead of print]

Beynon RA, Lang S, Schimansky S, Penfold CM, Waylen A, Thomas SJ, Pawlita M, Waterboer T T, Martin RM, May M, Ness AR. Tobacco smoking and alcohol drinking at diagnosis of head and neck cancer and all-cause mortality: Results from Head and Neck 5000, a prospective observational cohort of people with head and neck cancer.

Int J Cancer. 2018 Apr 1. doi: 10.1002/ijc.31416. [Epub ahead of print] PMID: 29607493


Penfold CM, Thomas SJ, Waylen A, Ness AR. Change in alcohol and tobacco consumption after a diagnosis of head and neck cancer: Findings from Head and Neck 5000. Head Neck. 2018 Feb 27. doi: 10.1002/hed.25116. [Epub ahead of print] PMID: 29485685 [PubMed - as supplied by publisher]



Lesseur C, Diergaarde B, Olshan AF, Wunsch-Filho V, Ness AR, Liu G, Lacko M, Eluf-Nato J, Franceschi S, Lagiou P, Macfarlane GJ, Richiardi L, Boccia S, Polesei J, Kjaerheim K, Zaridze D, Johansson M, Weissler MC, Tajara EH, Nunes FD, de carvalho MB, Thomas S, Hung RJ, Peters WH, Herrero R, Cadoni G, Bueno-de-Mesquita HB, Steffen A, Agudo A, Shangina O, Xiao X, Gaborieau V, Chabrier A, Anantharaman D, Boffetta P, Amos CI, McKay JD, Brennan P.  Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.

Nature Genetics. 2016 Dec;48(12):1544-1550



Ness AR, Waylen A, Jeffreys M, Penfold C, Pring M, Leary S, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W
Worthington H, Nutting C, Fisher SO, Rogers SN, Thomas SJ; Head & Neck Study Team. Recruitment response rates and characteristics of 5511 enrolled in a perspective clinical cohort study head & neck 5000. Clinical Otolaryngology. 2015 Oct 5.



Ness AR, Waylen A, Hurley K, Jeffreys M, Penfold C, Pring M, Leary S, Allmark C, Toms S, Ring S, Peters TJ, Hollingworth W, Worthington H, Nutting C, Fisher S, Rogers SN, Thomas SJ, Head & Neck 5000 Study Team.   Establishing a large prospective clinical cohort in people with head and neck cancer as a biomedical resource : head and neck 5000. Bio Medical Central Cancer. 2014 Dec.17;14(1):973



Hughes C, Homer J, Bradley P, Nutting C, Ness A, Persson M, Jefferys M,Waylen, A, Leary S, Thomas S. An evaluation of current services available for people diagnosed with Head and Neck Cancer in the UK (2009-2010). Clinical Oncology. 2012 Dec; 24(10):e187-92.